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Research Article

Structural Basis of Cell Wall Cleavage by a Staphylococcal Autolysin

  • Sebastian Zoll,

    Affiliation: Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany

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  • Bernhard Pätzold equal contributor,

    equal contributor Contributed equally to this work with: Bernhard Pätzold, Martin Schlag

    Affiliation: Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany

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  • Martin Schlag equal contributor,

    equal contributor Contributed equally to this work with: Bernhard Pätzold, Martin Schlag

    Affiliation: Department of Microbial Genetics, Faculty of Biology, University of Tübingen, Tübingen, Germany

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  • Friedrich Götz,

    Affiliation: Department of Microbial Genetics, Faculty of Biology, University of Tübingen, Tübingen, Germany

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  • Hubert Kalbacher,

    Affiliations: Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany, Medical and Natural Sciences Research Center, Tübingen, Germany

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  • Thilo Stehle mail

    thilo.stehle@uni-tuebingen.de

    Affiliations: Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: March 12, 2010
  • DOI: 10.1371/journal.ppat.1000807

About the Authors

Sebastian Zoll, Bernhard Pätzold, Hubert Kalbacher, Thilo Stehle
Interfaculty Institute for Biochemistry, University of Tübingen, Tübingen, Germany
Martin Schlag, Friedrich Götz
Department of Microbial Genetics, Faculty of Biology, University of Tübingen, Tübingen, Germany
Hubert Kalbacher
Medical and Natural Sciences Research Center, Tübingen, Germany
Thilo Stehle
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Corresponding Author

Email: thilo.stehle@uni-tuebingen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SZ BP FG HK TS. Performed the experiments: SZ BP MS TS. Analyzed the data: SZ BP TS. Contributed reagents/materials/analysis tools: MS HK. Wrote the paper: SZ BP FG HK TS.