Advertisement
Research Article

Human Cytomegalovirus Protein pUL117 Targets the Mini-Chromosome Maintenance Complex and Suppresses Cellular DNA Synthesis

  • Zhikang Qian,

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    X
  • Van Leung-Pineda,

    Affiliation: Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    X
  • Baoqin Xuan,

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    X
  • Helen Piwnica-Worms,

    Affiliations: Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America, Department of Internal Medicine, Washington University School of Medicine, Saint Louis, Missouri, United States of America, Howard Hughes Medical Institute, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    X
  • Dong Yu mail

    dongyu@borcim.wustl.edu

    Affiliation: Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America

    X
  • Published: March 19, 2010
  • DOI: 10.1371/journal.ppat.1000814

About the Authors

Zhikang Qian, Baoqin Xuan, Dong Yu
Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
Van Leung-Pineda, Helen Piwnica-Worms
Department of Cell Biology and Physiology, Washington University School of Medicine, Saint Louis, Missouri, United States of America
Helen Piwnica-Worms
Department of Internal Medicine, Washington University School of Medicine, Saint Louis, Missouri, United States of America
Helen Piwnica-Worms
Howard Hughes Medical Institute, Washington University School of Medicine, Saint Louis, Missouri, United States of America

Corresponding Author

Email: dongyu@borcim.wustl.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: ZQ VLP HPW DY. Performed the experiments: ZQ VLP BX. Analyzed the data: ZQ VLP BX HPW DY. Contributed reagents/materials/analysis tools: HPW. Wrote the paper: ZQ DY.