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Research Article

MicroRNA Antagonism of the Picornaviral Life Cycle: Alternative Mechanisms of Interference

  • Elizabeth J. Kelly,

    Affiliation: Department of Molecular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America

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  • Elizabeth M. Hadac,

    Affiliation: Department of Molecular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America

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  • Bryan R. Cullen,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

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  • Stephen J. Russell mail

    sjr@mayo.edu

    Affiliation: Department of Molecular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America

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  • Published: March 19, 2010
  • DOI: 10.1371/journal.ppat.1000820

About the Authors

Elizabeth J. Kelly, Elizabeth M. Hadac, Stephen J. Russell
Department of Molecular Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, United States of America
Bryan R. Cullen
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

Corresponding Author

Email: sjr@mayo.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EJK. Performed the experiments: EJK EMH. Analyzed the data: EJK SJR. Contributed reagents/materials/analysis tools: EMH. Wrote the paper: EJK BRC SJR. Supervised the project: SJR.