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Research Article

Escape of HIV-1-Infected Dendritic Cells from TRAIL-Mediated NK Cell Cytotoxicity during NK-DC Cross-Talk—A Pivotal Role of HMGB1

  • Marie-Thérèse Melki,

    Affiliation: Institut Pasteur, Antiviral Immunity, Biotherapy and Vaccine Unit, Paris, France

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  • Héla Saïdi,

    Affiliation: Institut Pasteur, Antiviral Immunity, Biotherapy and Vaccine Unit, Paris, France

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  • Alexandre Dufour,

    Affiliation: Institut Pasteur, Quantitative Image Analysis Unit, CNRS URA 2582, Paris, France

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  • Jean-Christophe Olivo-Marin,

    Affiliation: Institut Pasteur, Quantitative Image Analysis Unit, CNRS URA 2582, Paris, France

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  • Marie-Lise Gougeon mail

    mlgougeo@pasteur.fr

    Affiliation: Institut Pasteur, Antiviral Immunity, Biotherapy and Vaccine Unit, Paris, France

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  • Published: April 15, 2010
  • DOI: 10.1371/journal.ppat.1000862

About the Authors

Marie-Thérèse Melki, Héla Saïdi, Marie-Lise Gougeon
Institut Pasteur, Antiviral Immunity, Biotherapy and Vaccine Unit, Paris, France
Alexandre Dufour, Jean-Christophe Olivo-Marin
Institut Pasteur, Quantitative Image Analysis Unit, CNRS URA 2582, Paris, France

Corresponding Author

Email: mlgougeo@pasteur.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MTM HS MLG. Performed the experiments: MTM HS AD. Analyzed the data: MTM HS AD JCOM MLG. Wrote the paper: MTM HS AD JCOM MLG.