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Research Article

Galectin-9/TIM-3 Interaction Regulates Virus-Specific Primary and Memory CD8+ T Cell Response

  • Sharvan Sehrawat,

    Affiliation: Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America

    Current address: Whitehead Institute of Biomedical Research, Cambridge, Massachusetts, United States of America

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  • Pradeep B. J. Reddy,

    Affiliation: Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Naveen Rajasagi,

    Affiliation: Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Amol Suryawanshi,

    Affiliation: Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Mitsuomi Hirashima,

    Affiliation: Department of Immunology & Immunopathology, Faculty of Medicine, Kagawa University, Kagawa, Japan

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  • Barry T. Rouse mail

    btr@utk.edu

    Affiliation: Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America

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  • Published: May 06, 2010
  • DOI: 10.1371/journal.ppat.1000882

About the Authors

Sharvan Sehrawat, Pradeep B. J. Reddy, Naveen Rajasagi, Amol Suryawanshi, Barry T. Rouse
Department of Pathobiology, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, United States of America
Mitsuomi Hirashima
Department of Immunology & Immunopathology, Faculty of Medicine, Kagawa University, Kagawa, Japan

Corresponding Author

Email: btr@utk.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SS BTR. Performed the experiments: SS PBJR NR AS. Analyzed the data: SS PBJR NR AS. Contributed reagents/materials/analysis tools: MH. Wrote the paper: SS BTR. Overall supervision: BTR.