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Research Article

Chlamydia pneumoniae Is Genetically Diverse in Animals and Appears to Have Crossed the Host Barrier to Humans on (At Least) Two Occasions

  • Candice M. Mitchell,

    Affiliation: Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, Kelvin Grove, Queensland, Australia

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  • Susan Hutton,

    Affiliation: Menzies School of Health Research, Royal Darwin Hospital Campus, Casuarina, Northern Territory, Australia

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  • Garry S. A. Myers,

    Affiliation: Institute for Genome Sciences, University of Maryland, Baltimore, Maryland, United States of America

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  • Robert Brunham,

    Affiliation: British Columbia Centre for Disease Control, University of British Columbia, Vancouver, British Columbia, Canada

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  • Peter Timms mail

    p.timms@qut.edu.au

    Affiliation: Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, Kelvin Grove, Queensland, Australia

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  • Published: May 20, 2010
  • DOI: 10.1371/journal.ppat.1000903

About the Authors

Candice M. Mitchell, Peter Timms
Institute of Health and Biomedical Innovation, School of Life Sciences, Queensland University of Technology, Kelvin Grove, Queensland, Australia
Susan Hutton
Menzies School of Health Research, Royal Darwin Hospital Campus, Casuarina, Northern Territory, Australia
Garry S. A. Myers
Institute for Genome Sciences, University of Maryland, Baltimore, Maryland, United States of America
Robert Brunham
British Columbia Centre for Disease Control, University of British Columbia, Vancouver, British Columbia, Canada

Corresponding Author

Email: p.timms@qut.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CMM PT. Performed the experiments: CMM. Analyzed the data: CMM GSAM PT. Contributed reagents/materials/analysis tools: SH. Wrote the paper: CMM RB PT. Carried out the genetic studies (PCR and gene sequencing), data analysis, manuscript writing: CMM. Revised the article critically for important intellectual content: SH RB. Managed the genome sequencing: GSAM. Conceived of the study and participated in its design, and contributed to the intellectual content of the manuscript: PT. All authors read and approved the final manuscript.