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Research Article

Insight into the Mechanisms of Adenovirus Capsid Disassembly from Studies of Defensin Neutralization

  • Jason G. Smith equal contributor,

    equal contributor Contributed equally to this work with: Jason G. Smith, Mariena Silvestry

    Affiliation: Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

    Current address: Department of Microbiology, University of Washington School of Medicine, Seattle, Washington, United States of America

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  • Mariena Silvestry equal contributor,

    equal contributor Contributed equally to this work with: Jason G. Smith, Mariena Silvestry

    Affiliation: Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Steffen Lindert,

    Affiliation: Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Wuyuan Lu,

    Affiliation: Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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  • Glen R. Nemerow,

    Affiliation: Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America

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  • Phoebe L. Stewart mail

    phoebe.stewart@vanderbilt.edu

    Affiliation: Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

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  • Published: June 24, 2010
  • DOI: 10.1371/journal.ppat.1000959

About the Authors

Jason G. Smith, Glen R. Nemerow
Department of Immunology and Microbial Science, The Scripps Research Institute, La Jolla, California, United States of America
Mariena Silvestry, Steffen Lindert, Phoebe L. Stewart
Department of Molecular Physiology and Biophysics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
Wuyuan Lu
Institute of Human Virology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

Corresponding Author

Email: phoebe.stewart@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JGS GRN PLS. Performed the experiments: JGS MS SL. Analyzed the data: JGS MS GRN PLS. Contributed reagents/materials/analysis tools: WL. Wrote the paper: JGS GRN PLS.