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Research Article

Transduction of Human T Cells with a Novel T-Cell Receptor Confers Anti-HCV Reactivity

  • Yi Zhang,

    Affiliation: Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Yeuying Liu,

    Affiliation: Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Kelly M. Moxley,

    Affiliation: Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Lucy Golden-Mason,

    Affiliation: Division of Gastroenterology & Hepatology, Hepatitis C Center & Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America

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  • Michael G. Hughes Jr,

    Affiliation: Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Tongxin Liu,

    Affiliation: Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Mirjam H. M. Heemskerk,

    Affiliation: Laboratory of Experimental Hematology, Department of Hematology, Leiden University Medical Center Leiden, the Netherlands

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  • Hugo R. Rosen,

    Affiliation: Division of Gastroenterology & Hepatology, Hepatitis C Center & Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America

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  • Michael I. Nishimura mail

    nishimum@musc.edu

    Affiliation: Division of General Surgery, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

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  • Published: July 29, 2010
  • DOI: 10.1371/journal.ppat.1001018

About the Authors

Yi Zhang, Yeuying Liu, Kelly M. Moxley, Michael G. Hughes Jr, Tongxin Liu
Division of Transplantation, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America
Lucy Golden-Mason, Hugo R. Rosen
Division of Gastroenterology & Hepatology, Hepatitis C Center & Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado, United States of America
Mirjam H. M. Heemskerk
Laboratory of Experimental Hematology, Department of Hematology, Leiden University Medical Center Leiden, the Netherlands
Michael I. Nishimura
Division of General Surgery, Department of Surgery, Medical University of South Carolina, Hollings Cancer Center, Charleston, South Carolina, United States of America

Corresponding Author

Email: nishimum@musc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YZ MGH MIN. Performed the experiments: YZ YL KMM MGH TL. Analyzed the data: YZ KMM MIN. Contributed reagents/materials/analysis tools: YZ LGM MGH MHMH HRR. Wrote the paper: YZ HRR MIN.