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Research Article

The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement

  • Lisa A. Lewis mail,

    lisa.lewis@umassmed.edu

    Affiliation: Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Jutamas Ngampasutadol,

    Affiliation: Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Ruth Wallace,

    Affiliation: Trinity College, Dublin, Ireland

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  • Jane E. A. Reid,

    Affiliation: Trinity College, Dublin, Ireland

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  • Ulrich Vogel,

    Affiliation: Universität Würzburg, Würzburg, Germany

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  • Sanjay Ram

    Affiliation: Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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  • Published: July 29, 2010
  • DOI: 10.1371/journal.ppat.1001027

About the Authors

Lisa A. Lewis, Jutamas Ngampasutadol, Sanjay Ram
Division of Infectious Diseases and Immunology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Ruth Wallace, Jane E. A. Reid
Trinity College, Dublin, Ireland
Ulrich Vogel
Universität Würzburg, Würzburg, Germany

Corresponding Author

Email: lisa.lewis@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LAL SR. Performed the experiments: LAL JN RW JEAR SR. Analyzed the data: LAL UV SR. Contributed reagents/materials/analysis tools: LAL UV SR. Wrote the paper: LAL SR. Approved submitted manuscript: JN RW JEAR UV. Aided in critical revisions of the manuscript for important intellectual content: UV.