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Research Article

Structural Alterations in a Component of Cytochrome c Oxidase and Molecular Evolution of Pathogenic Neisseria in Humans

  • Marina Aspholm ,

    Affiliations: Department of Molecular Biosciences, University of Oslo, Oslo, Norway, Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway

    Co-first authors, contributed equally to this work.

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  • Finn Erik Aas ,

    Affiliations: Department of Molecular Biosciences, University of Oslo, Oslo, Norway, Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway

    Co-first authors, contributed equally to this work.

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  • Odile B. Harrison,

    Affiliation: Department of Zoology, University of Oxford, Oxford, United Kingdom

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  • Diana Quinn,

    Affiliation: Department of Biology (Area 10), University of York, Heslington, York, United Kingdom

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  • Åshild Vik,

    Affiliations: Department of Molecular Biosciences, University of Oslo, Oslo, Norway, Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway

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  • Raimonda Viburiene,

    Affiliations: Department of Molecular Biosciences, University of Oslo, Oslo, Norway, Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway

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  • Tone Tønjum,

    Affiliations: Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway, Institute of Microbiology, University of Oslo, Oslo, Norway

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  • James Moir,

    Affiliation: Department of Biology (Area 10), University of York, Heslington, York, United Kingdom

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  • Martin C. J. Maiden,

    Affiliation: Department of Zoology, University of Oxford, Oxford, United Kingdom

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  • Michael Koomey mail

    j.m.koomey@imbv.uio.no

    Affiliations: Department of Molecular Biosciences, University of Oslo, Oslo, Norway, Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway

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  • Published: August 19, 2010
  • DOI: 10.1371/journal.ppat.1001055

About the Authors

Marina Aspholm, Finn Erik Aas, Åshild Vik, Raimonda Viburiene, Michael Koomey
Department of Molecular Biosciences, University of Oslo, Oslo, Norway
Marina Aspholm, Finn Erik Aas, Åshild Vik, Raimonda Viburiene, Tone Tønjum, Michael Koomey
Centre for Molecular Biology and Neuroscience, University of Oslo, Oslo, Norway
Odile B. Harrison, Martin C. J. Maiden
Department of Zoology, University of Oxford, Oxford, United Kingdom
Diana Quinn, James Moir
Department of Biology (Area 10), University of York, Heslington, York, United Kingdom
Tone Tønjum
Institute of Microbiology, University of Oslo, Oslo, Norway

Corresponding Author

Email: j.m.koomey@imbv.uio.no

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MA FEA OBH JM MCJM MK. Performed the experiments: MA FEA OBH DQ RV. Analyzed the data: MA FEA OBH DQ RV JM MCJM MK. Contributed reagents/materials/analysis tools: ÅV TT JM MCJM MK. Wrote the paper: MA FEA OBH TT JM MCJM MK.