Advertisement
Research Article

Enterohemorrhagic E. coli Requires N-WASP for Efficient Type III Translocation but Not for EspFU-Mediated Actin Pedestal Formation

  • Didier Vingadassalom equal contributor,

    equal contributor Contributed equally to this work with: Didier Vingadassalom, Kenneth G. Campellone

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Kenneth G. Campellone equal contributor,

    equal contributor Contributed equally to this work with: Didier Vingadassalom, Kenneth G. Campellone

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    Current address: Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California, United States of America

    X
  • Michael J. Brady,

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Brian Skehan,

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Scott E. Battle,

    Affiliation: Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Douglas Robbins,

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Archana Kapoor,

    Affiliation: Department of Medicine and Immunology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • Gail Hecht,

    Affiliation: Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States of America

    X
  • Scott B. Snapper,

    Affiliation: Department of Medicine and Immunology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

    X
  • John M. Leong mail

    John.Leong@umassmed.edu

    Affiliation: Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

    X
  • Published: August 19, 2010
  • DOI: 10.1371/journal.ppat.1001056

About the Authors

Didier Vingadassalom, Kenneth G. Campellone, Michael J. Brady, Brian Skehan, Douglas Robbins, John M. Leong
Department of Molecular Genetics and Microbiology, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
Scott E. Battle, Gail Hecht
Section of Digestive Diseases and Nutrition, University of Illinois at Chicago, Chicago, Illinois, United States of America
Archana Kapoor, Scott B. Snapper
Department of Medicine and Immunology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Corresponding Author

Email: John.Leong@umassmed.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DV KGC MJB SBS JML. Performed the experiments: DV KGC MJB BS SEB DR AK. Analyzed the data: DV KGC MJB BS SEB AK GH JML. Contributed reagents/materials/analysis tools: GH SBS JML. Wrote the paper: DV KGC MJB JML.