Advertisement
Research Article

Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

  • Sun-Hee Ahn,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Hitesh Deshmukh,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Nicole Johnson,

    Affiliation: Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Lindsay G. Cowell,

    Affiliation: Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Thomas H. Rude,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • William K. Scott,

    Affiliation: Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

    X
  • Charlotte L. Nelson,

    Affiliation: Duke Clinical Research Institute, Durham, North Carolina, United States of America

    X
  • Aimee K. Zaas,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Douglas A. Marchuk,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Sehoon Keum,

    Affiliation: Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Supaporn Lamlertthon,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Batu K. Sharma-Kuinkel,

    Affiliation: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America

    X
  • Gregory D. Sempowski,

    Affiliation: Duke Human Vaccine Institute, Durham, North Carolina, United States of America

    X
  • Vance G. Fowler Jr mail

    fowle003@mc.duke.edu

    Affiliations: Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America, Duke Clinical Research Institute, Durham, North Carolina, United States of America

    X
  • Published: September 02, 2010
  • DOI: 10.1371/journal.ppat.1001088

About the Authors

Sun-Hee Ahn, Hitesh Deshmukh, Thomas H. Rude, Aimee K. Zaas, Supaporn Lamlertthon, Batu K. Sharma-Kuinkel, Vance G. Fowler Jr
Department of Medicine, Duke University Medical Center, Durham, North Carolina, United States of America
Nicole Johnson, Lindsay G. Cowell
Department of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, North Carolina, United States of America
William K. Scott
Dr. John T. Macdonald Foundation Department of Human Genetics and John P. Hussman Institute for Human Genomics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America
Charlotte L. Nelson, Vance G. Fowler Jr
Duke Clinical Research Institute, Durham, North Carolina, United States of America
Douglas A. Marchuk, Sehoon Keum
Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, North Carolina, United States of America
Gregory D. Sempowski
Duke Human Vaccine Institute, Durham, North Carolina, United States of America

Corresponding Author

Email: fowle003@mc.duke.edu

Competing Interests

Dr. Fowler has served as a consultant for Astellas, Cubist, Inhibitex, Merck, Johnson & Johnson, Leo Pharmaceuticals, NovaDigm, The Medicines Company, Baxter Pharmaceuticals & Biosynexus; has received grant or research support from Astellas, Cubist, Merck, Theravance, Inhibitex, Cerexa, Pfizer, Novartis, Advanced Liquid Logic and National Institute of Health; has received honoraria from Arpida, Astellas, Cubist, Inhibitex, Merck, Pfizer, Targanta, Theravance, Ortho-McNeil, Novartis & Vertex Pharmaceuticals; has served on an advisory committee for Cubist; is employed by Duke University; and has served as a speaker's bureau for Cubist.

Author Contributions

Conceived and designed the experiments: SHA HD NJ LGC WKS AKZ DAM SK SL BKSK VGF. Performed the experiments: SHA HD THR. Analyzed the data: SHA HD NJ LGC CLN GDS VGF. Wrote the paper: SHA HD LGC VGF.