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Research Article

A Novel Family of Toxoplasma IMC Proteins Displays a Hierarchical Organization and Functions in Coordinating Parasite Division

  • Josh R. Beck,

    Affiliation: Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

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  • Imilce A. Rodriguez-Fernandez,

    Affiliation: Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

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  • Jessica Cruz de Leon,

    Affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, United States of America

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  • My-Hang Huynh,

    Affiliation: Department of Microbiology and Immunology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

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  • Vern B. Carruthers,

    Affiliation: Department of Microbiology and Immunology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

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  • Naomi S. Morrissette,

    Affiliation: Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, United States of America

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  • Peter J. Bradley mail

    pbradley@ucla.edu

    Affiliation: Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America

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  • Published: September 09, 2010
  • DOI: 10.1371/journal.ppat.1001094

About the Authors

Josh R. Beck, Imilce A. Rodriguez-Fernandez, Peter J. Bradley
Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, Los Angeles, California, United States of America
Jessica Cruz de Leon, Naomi S. Morrissette
Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California, United States of America
My-Hang Huynh, Vern B. Carruthers
Department of Microbiology and Immunology, University of Michigan School of Medicine, Ann Arbor, Michigan, United States of America

Corresponding Author

Email: pbradley@ucla.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRB PJB. Performed the experiments: JRB IARF JCdL. Analyzed the data: JRB NSM PJB. Contributed reagents/materials/analysis tools: JRB MHH VBC NSM PJB. Wrote the paper: JRB NSM PJB.