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Research Article

Steric Shielding of Surface Epitopes and Impaired Immune Recognition Induced by the Ebola Virus Glycoprotein

  • Joseph R. Francica,

    Affiliation: Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Angel Varela-Rohena,

    Affiliation: Department of Pathology and Lab Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Andrew Medvec,

    Affiliation: Department of Pathology and Lab Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Gabriela Plesa,

    Affiliation: Department of Pathology and Lab Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • James L. Riley,

    Affiliation: Department of Pathology and Lab Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Paul Bates mail

    pbates@mail.med.upenn.edu

    Affiliation: Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

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  • Published: September 09, 2010
  • DOI: 10.1371/journal.ppat.1001098

About the Authors

Joseph R. Francica, Paul Bates
Department of Microbiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
Angel Varela-Rohena, Andrew Medvec, Gabriela Plesa, James L. Riley
Department of Pathology and Lab Medicine and Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America

Corresponding Author

Email: pbates@mail.med.upenn.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JRF AVR JLR PB. Performed the experiments: JRF AVR AM GP. Analyzed the data: JRF AVR AM JLR PB. Contributed reagents/materials/analysis tools: JRF AVR GP PB. Wrote the paper: JRF PB.