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Research Article

HLA Class I Binding of HBZ Determines Outcome in HTLV-1 Infection

  • Aidan MacNamara,

    Affiliation: Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Aileen Rowan,

    Affiliation: Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Silva Hilburn,

    Affiliation: Section of Infectious Diseases, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Ulrich Kadolsky,

    Affiliation: Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Hiroshi Fujiwara,

    Affiliation: Department of Bioregulatory Medicine, Graduate School of Medicine, Ehime University, and Ehime University Proteomedicine Research Center, Toh-on city, Ehime, Japan

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  • Koichiro Suemori,

    Affiliation: Department of Bioregulatory Medicine, Graduate School of Medicine, Ehime University, and Ehime University Proteomedicine Research Center, Toh-on city, Ehime, Japan

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  • Masaki Yasukawa,

    Affiliation: Department of Bioregulatory Medicine, Graduate School of Medicine, Ehime University, and Ehime University Proteomedicine Research Center, Toh-on city, Ehime, Japan

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  • Graham Taylor,

    Affiliation: Section of Infectious Diseases, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Charles R. M. Bangham,

    Affiliation: Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Becca Asquith mail

    b.asquith@ic.ac.uk

    Affiliation: Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom

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  • Published: September 23, 2010
  • DOI: 10.1371/journal.ppat.1001117

About the Authors

Aidan MacNamara, Aileen Rowan, Ulrich Kadolsky, Charles R. M. Bangham, Becca Asquith
Department of Immunology, Faculty of Medicine, Imperial College, London, United Kingdom
Silva Hilburn, Graham Taylor
Section of Infectious Diseases, Faculty of Medicine, Imperial College, London, United Kingdom
Hiroshi Fujiwara, Koichiro Suemori, Masaki Yasukawa
Department of Bioregulatory Medicine, Graduate School of Medicine, Ehime University, and Ehime University Proteomedicine Research Center, Toh-on city, Ehime, Japan

Corresponding Author

Email: b.asquith@ic.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: UK BA. Performed the experiments: AM AR SH GT. Analyzed the data: AM GT CRMB BA. Contributed reagents/materials/analysis tools: HF KS MY. Wrote the paper: AM BA.