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Research Article

Direct Visualization of Peptide/MHC Complexes at the Surface and in the Intracellular Compartments of Cells Infected In Vivo by Leishmania major

  • Eric Muraille equal contributor,

    equal contributor Contributed equally to this work with: Eric Muraille, Pierre Gounon

    Affiliations: Institut de Pharmacologie Moléculaire et Cellulaire, INSERM U924, Valbonne, France, Université de Nice Sophia-Antipolis, Nice, France

    Current address: Laboratoire de Parasitologie, Université Libre de Bruxelles, Bruxelles, Belgium

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  • Pierre Gounon equal contributor,

    equal contributor Contributed equally to this work with: Eric Muraille, Pierre Gounon

    Affiliation: Université de Nice Sophia-Antipolis, Nice, France

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  • Julie Cazareth,

    Affiliations: Institut de Pharmacologie Moléculaire et Cellulaire, INSERM U924, Valbonne, France, Université de Nice Sophia-Antipolis, Nice, France, Institut de Pharmacologie Moléculaire et Cellulaire, UMR6097, Valbonne, France

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  • Johan Hoebeke,

    Affiliation: UPR 9021 CNRS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France

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  • Christoph Lippuner,

    Affiliation: Vetsuisse Faculty, University of Zürich, Zürich, Switzerland

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  • Ana Davalos-Misslitz,

    Affiliation: Department of Nephrology, Hannover Medical School, Hannover, Germany

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  • Toni Aebischer,

    Affiliation: Parasitology laboratory, Robert Koch Institute, Berlin, Germany

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  • Sylviane Muller,

    Affiliation: UPR 9021 CNRS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France

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  • Nicolas Glaichenhaus,

    Affiliations: Institut de Pharmacologie Moléculaire et Cellulaire, INSERM U924, Valbonne, France, Université de Nice Sophia-Antipolis, Nice, France

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  • Evelyne Mougneau mail

    Evelyne.Mougneau@unice.fr

    Affiliations: Institut de Pharmacologie Moléculaire et Cellulaire, INSERM U924, Valbonne, France, Université de Nice Sophia-Antipolis, Nice, France

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  • Published: October 14, 2010
  • DOI: 10.1371/journal.ppat.1001154

About the Authors

Eric Muraille, Julie Cazareth, Nicolas Glaichenhaus, Evelyne Mougneau
Institut de Pharmacologie Moléculaire et Cellulaire, INSERM U924, Valbonne, France
Eric Muraille, Pierre Gounon, Julie Cazareth, Nicolas Glaichenhaus, Evelyne Mougneau
Université de Nice Sophia-Antipolis, Nice, France
Julie Cazareth
Institut de Pharmacologie Moléculaire et Cellulaire, UMR6097, Valbonne, France
Johan Hoebeke, Sylviane Muller
UPR 9021 CNRS, Institut de Biologie Moléculaire et Cellulaire, Strasbourg, France
Christoph Lippuner
Vetsuisse Faculty, University of Zürich, Zürich, Switzerland
Ana Davalos-Misslitz
Department of Nephrology, Hannover Medical School, Hannover, Germany
Toni Aebischer
Parasitology laboratory, Robert Koch Institute, Berlin, Germany

Corresponding Author

Email: Evelyne.Mougneau@unice.fr

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: E. Muraille, P. Gounon, J. Hoebeke, N. Glaichenhaus, E. Mougneau. Performed the experiments: E. Muraille, P. Gounon, J. Cazareth, J. Hoebeke, E. Mougneau. Analyzed the data: E. Muraille, P. Gounon, J. Cazareth, J. Hoebeke, N. Glaichenhaus, E. Mougneau. Contributed reagents/materials/analysis tools: C. Lippuner, A. Davalos-Misslitz, T. Aebischer, S. Muller. Wrote the paper: N. Glaichenhaus, E. Mougneau.