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Research Article

Cryo Electron Tomography of Native HIV-1 Budding Sites

  • Lars-Anders Carlson,

    Affiliations: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany, Department of Molecular Structural Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany

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  • Alex de Marco,

    Affiliation: Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

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  • Heike Oberwinkler,

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

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  • Anja Habermann,

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

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  • John A. G. Briggs,

    Affiliation: Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany

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  • Hans-Georg Kräusslich mail,

    hans-georg.kraeusslich@med.uni-heidelberg.de (HGK); kay@strubi.ox.ac.uk (KG)

    Affiliation: Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany

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  • Kay Grünewald mail

    hans-georg.kraeusslich@med.uni-heidelberg.de (HGK); kay@strubi.ox.ac.uk (KG)

    Affiliations: Department of Molecular Structural Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany, Oxford Particle Imaging Centre, Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

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  • Published: November 24, 2010
  • DOI: 10.1371/journal.ppat.1001173

About the Authors

Lars-Anders Carlson, Heike Oberwinkler, Anja Habermann, Hans-Georg Kräusslich
Department of Infectious Diseases, Virology, Universitätsklinikum Heidelberg, Heidelberg, Germany
Lars-Anders Carlson, Kay Grünewald
Department of Molecular Structural Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany
Alex de Marco, John A. G. Briggs
Structural and Computational Biology Unit, European Molecular Biology Laboratory, Heidelberg, Germany
Kay Grünewald
Oxford Particle Imaging Centre, Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LAC JAGB HGK KG. Performed the experiments: LAC AdM HO AH. Analyzed the data: LAC AdM JAGB HGK KG. Wrote the paper: LAC JAGB HGK KG.