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Research Article

Leishmania major Survival in Selective Phlebotomus papatasi Sand Fly Vector Requires a Specific SCG-Encoded Lipophosphoglycan Galactosylation Pattern

  • Deborah E. Dobson mail,

    dedobson@borcim.wustl.edu

    Affiliation: Department of Molecular Microbiology, Washington University Medical School, St. Louis, Missouri, United States of America

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  • Shaden Kamhawi,

    Affiliation: Laboratory of Parasitic Diseases, Intracellular Parasite Biology Section, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Phillip Lawyer,

    Affiliation: Laboratory of Parasitic Diseases, Intracellular Parasite Biology Section, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Salvatore J. Turco,

    Affiliation: Department of Molecular and Cellular Biochemistry, University of Kentucky Medical Center, Lexington, Kentucky, United States of America

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  • Stephen M. Beverley,

    Affiliation: Department of Molecular Microbiology, Washington University Medical School, St. Louis, Missouri, United States of America

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  • David L. Sacks

    Affiliation: Laboratory of Parasitic Diseases, Intracellular Parasite Biology Section, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Published: November 11, 2010
  • DOI: 10.1371/journal.ppat.1001185

About the Authors

Deborah E. Dobson, Stephen M. Beverley
Department of Molecular Microbiology, Washington University Medical School, St. Louis, Missouri, United States of America
Shaden Kamhawi, Phillip Lawyer, David L. Sacks
Laboratory of Parasitic Diseases, Intracellular Parasite Biology Section, National Institutes of Health, Bethesda, Maryland, United States of America
Salvatore J. Turco
Department of Molecular and Cellular Biochemistry, University of Kentucky Medical Center, Lexington, Kentucky, United States of America

Corresponding Author

Email: dedobson@borcim.wustl.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DED SMB DLS. Performed the experiments: DED SK PL SJT DLS. Analyzed the data: DED SJT SMB DLS. Wrote the paper: DED SMB DLS.