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Research Article

Legionella Metaeffector Exploits Host Proteasome to Temporally Regulate Cognate Effector

  • Tomoko Kubori,

    Affiliations: Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan, Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan

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  • Naoaki Shinzawa,

    Affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

    Current address: Department of Molecular Parasitology, Ehime University Graduate School of Medicine, Shitsukawa, Toon, Ehime, Japan

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  • Hirotaka Kanuka,

    Affiliation: National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

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  • Hiroki Nagai mail

    hnagai@biken.osaka-u.ac.jp

    Affiliation: Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan

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  • Published: December 02, 2010
  • DOI: 10.1371/journal.ppat.1001216

About the Authors

Tomoko Kubori, Hiroki Nagai
Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan
Tomoko Kubori
Graduate School of Frontier Biosciences, Osaka University, Suita, Osaka, Japan
Naoaki Shinzawa, Hirotaka Kanuka
National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

Corresponding Author

Email: hnagai@biken.osaka-u.ac.jp

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TK NS HK HN. Performed the experiments: TK NS HN. Analyzed the data: TK NS HN. Wrote the paper: TK NS HK HN.