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Research Article

Imaging Single Retrovirus Entry through Alternative Receptor Isoforms and Intermediates of Virus-Endosome Fusion

  • Naveen K. Jha,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    Current address: Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America.

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  • Olga Latinovic,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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  • Erik Martin,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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  • Gennadiy Novitskiy,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

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  • Mariana Marin,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    Current address: Division of Pediatric Infectious Diseases, Emory University Children's Center, Atlanta, Georgia, United States of America.

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  • Kosuke Miyauchi,

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    Current address: AIDS Research Center, National Institute of Infectious Diseases, Tokyo, Japan.

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  • John Naughton,

    Affiliation: Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • John A. T. Young,

    Affiliation: Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, California, United States of America

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  • Gregory B. Melikyan mail

    gmeliki@emory.edu

    Affiliation: Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America

    Current address: Division of Pediatric Infectious Diseases, Emory University Children's Center, Atlanta, Georgia, United States of America.

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  • Published: January 20, 2011
  • DOI: 10.1371/journal.ppat.1001260

About the Authors

Naveen K. Jha, Olga Latinovic, Erik Martin, Gennadiy Novitskiy, Mariana Marin, Kosuke Miyauchi, Gregory B. Melikyan
Institute of Human Virology and Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
John Naughton, John A. T. Young
Nomis Center for Immunobiology and Microbial Pathogenesis, The Salk Institute for Biological Studies, La Jolla, California, United States of America

Corresponding Author

Email: gmeliki@emory.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GBM. Performed the experiments: NKJ OL EM GN MM KM JN. Analyzed the data: NKJ OL EM GN MM KM JN GBM. Contributed reagents/materials/analysis tools: JATY. Wrote the paper: MM JATY GBM.