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Research Article

Entrapment of Viral Capsids in Nuclear PML Cages Is an Intrinsic Antiviral Host Defense against Varicella-Zoster Virus

  • Mike Reichelt mail,

    reichelt@stanford.edu

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Li Wang,

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Marvin Sommer,

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • John Perrino,

    Affiliation: Cell Sciences Imaging Facility, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Adel M. Nour,

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Nandini Sen,

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Armin Baiker,

    Affiliation: Department of Virology, Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

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  • Leigh Zerboni,

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

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  • Ann M. Arvin

    Affiliation: Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America

    X
  • Published: February 03, 2011
  • DOI: 10.1371/journal.ppat.1001266

About the Authors

Mike Reichelt, Li Wang, Marvin Sommer, Adel M. Nour, Nandini Sen, Leigh Zerboni, Ann M. Arvin
Departments of Pediatrics and Microbiology & Immunology, Stanford University School of Medicine, Stanford, California, United States of America
John Perrino
Cell Sciences Imaging Facility, Stanford University School of Medicine, Stanford, California, United States of America
Armin Baiker
Department of Virology, Max von Pettenkofer-Institute, Ludwig-Maximilians-University, Munich, Germany

Corresponding Author

Email: reichelt@stanford.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MR LW MS AMA. Performed the experiments: MR LW MS JP AMN. Analyzed the data: MR LW AMA. Contributed reagents/materials/analysis tools: MS JP AMN NS AB LZ. Wrote the paper: MR AMA.