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Research Article

Charge-Surrounded Pockets and Electrostatic Interactions with Small Ions Modulate the Activity of Retroviral Fusion Proteins

  • Daniel Lamb equal contributor,

    equal contributor Contributed equally to this work with: Daniel Lamb, Alexander W. Schüttelkopf

    Affiliation: The Biomedical Research Institute, College of Medicine, Ninewells Hospital, The University of Dundee, Dundee, United Kingdom

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  • Alexander W. Schüttelkopf equal contributor,

    equal contributor Contributed equally to this work with: Daniel Lamb, Alexander W. Schüttelkopf

    Affiliation: Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee, United Kingdom

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  • Daan M. F. van Aalten ,

    Affiliation: Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee, United Kingdom

    The laboratories of these authors contributed equally to this study.

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  • David W. Brighty mail

    d.w.brighty@dundee.ac.uk

    Affiliation: The Biomedical Research Institute, College of Medicine, Ninewells Hospital, The University of Dundee, Dundee, United Kingdom

    The laboratories of these authors contributed equally to this study.

    X
  • Published: February 03, 2011
  • DOI: 10.1371/journal.ppat.1001268

About the Authors

Daniel Lamb, David W. Brighty
The Biomedical Research Institute, College of Medicine, Ninewells Hospital, The University of Dundee, Dundee, United Kingdom
Alexander W. Schüttelkopf, Daan M. F. van Aalten
Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee, United Kingdom

Corresponding Author

Email: d.w.brighty@dundee.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DWB. Performed the experiments: DL AWS. Analyzed the data: DL AWS DMFvA DWB. Contributed reagents/materials/analysis tools: AWS DMFvA. Wrote the paper: DL DWB.