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Research Article

Expression of P. falciparum var Genes Involves Exchange of the Histone Variant H2A.Z at the Promoter

  • Michaela Petter,

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

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  • Chin Chin Lee,

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

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  • Timothy J. Byrne,

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

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  • Katja E. Boysen,

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

    Current address: Department of Parasitology, Max-Planck-Institute of Infection Biology, Berlin, Germany

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  • Jennifer Volz,

    Affiliation: The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia

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  • Stuart A. Ralph,

    Affiliation: Department of Biochemistry and Molecular Biology, Bio21 Molecular Sciences and Biotechnology Institute, University of Melbourne, Melbourne, Australia

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  • Alan F. Cowman,

    Affiliations: The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia, Department of Medical Biology, University of Melbourne, Melbourne, Australia

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  • Graham V. Brown,

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

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  • Michael F. Duffy mail

    mduffy@unimelb.edu.au

    Affiliation: Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia

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  • Published: February 17, 2011
  • DOI: 10.1371/journal.ppat.1001292

About the Authors

Michaela Petter, Chin Chin Lee, Timothy J. Byrne, Katja E. Boysen, Graham V. Brown, Michael F. Duffy
Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia
Jennifer Volz, Alan F. Cowman
The Walter and Eliza Hall Institute of Medical Research, Melbourne, Australia
Stuart A. Ralph
Department of Biochemistry and Molecular Biology, Bio21 Molecular Sciences and Biotechnology Institute, University of Melbourne, Melbourne, Australia
Alan F. Cowman
Department of Medical Biology, University of Melbourne, Melbourne, Australia

Corresponding Author

Email: mduffy@unimelb.edu.au

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MP MFD. Performed the experiments: MP CCL TJB KEB JV SAR MFD. Analyzed the data: MP MFD. Contributed reagents/materials/analysis tools: MP JV SAR AFC GVB MFD. Wrote the paper: MP GVB MFD.