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Research Article

Human Macrophage Responses to Clinical Isolates from the Mycobacterium tuberculosis Complex Discriminate between Ancient and Modern Lineages

  • Damien Portevin mail,

    dportev@nimr.mrc.ac.uk

    Affiliation: Mycobacterial Research Division, MRC National Institute for Medical Research, London, United Kingdom

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  • Sébastien Gagneux,

    Affiliations: Mycobacterial Research Division, MRC National Institute for Medical Research, London, United Kingdom, Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

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  • Iñaki Comas,

    Affiliation: Mycobacterial Research Division, MRC National Institute for Medical Research, London, United Kingdom

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  • Douglas Young

    Affiliation: Mycobacterial Research Division, MRC National Institute for Medical Research, London, United Kingdom

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  • Published: March 03, 2011
  • DOI: 10.1371/journal.ppat.1001307

About the Authors

Damien Portevin, Sébastien Gagneux, Iñaki Comas, Douglas Young
Mycobacterial Research Division, MRC National Institute for Medical Research, London, United Kingdom
Sébastien Gagneux
Department of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland
Sébastien Gagneux
University of Basel, Basel, Switzerland

Corresponding Author

Email: dportev@nimr.mrc.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DP SG DY. Performed the experiments: DP. Analyzed the data: DP SG IC DY. Wrote the paper: DP SG IC DY.