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Research Article

On Being the Right Size: The Impact of Population Size and Stochastic Effects on the Evolution of Drug Resistance in Hospitals and the Community

  • Roger D. Kouyos equal contributor mail,

    equal contributor Contributed equally to this work with: Roger D. Kouyos, Pia Abel zur Wiesch

    rkouyos@princeton.edu

    Affiliations: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland, Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

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  • Pia Abel zur Wiesch equal contributor,

    equal contributor Contributed equally to this work with: Roger D. Kouyos, Pia Abel zur Wiesch

    Affiliation: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland

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  • Sebastian Bonhoeffer

    Affiliation: Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland

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  • Published: April 14, 2011
  • DOI: 10.1371/journal.ppat.1001334

About the Authors

Roger D. Kouyos, Pia Abel zur Wiesch, Sebastian Bonhoeffer
Institute of Integrative Biology, ETH Zurich, Zurich, Switzerland
Roger D. Kouyos
Department of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America

Corresponding Author

Email: rkouyos@princeton.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RDK PAzW SB. Performed the experiments: RDK. Analyzed the data: RDK. Contributed reagents/materials/analysis tools: SB. Wrote the paper: RDK PAzW SB.