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Research Article

Low Diversity Cryptococcus neoformans Variety grubii Multilocus Sequence Types from Thailand Are Consistent with an Ancestral African Origin

  • Sitali P. Simwami,

    Affiliation: Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Kantarawee Khayhan,

    Affiliations: CBS Fungal Biodiversity Centre, Utrecht, The Netherlands, Department of Microbiology and Parasitology, School of Medical Science, Naresuan University Phayao, Phayao, Thailand

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  • Daniel A. Henk,

    Affiliation: Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • David M. Aanensen,

    Affiliation: Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Teun Boekhout,

    Affiliation: CBS Fungal Biodiversity Centre, Utrecht, The Netherlands

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  • Ferry Hagen,

    Affiliation: CBS Fungal Biodiversity Centre, Utrecht, The Netherlands

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  • Annemarie E. Brouwer,

    Affiliations: Department of General Internal Medicine and Nijmegen University Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands, St. Elisabeth Hospital, Tilburg, The Netherlands

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  • Thomas S. Harrison,

    Affiliation: Department of Infectious Diseases, St George's Hospital Medical School, London, United Kingdom

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  • Christl A. Donnelly,

    Affiliation: Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Matthew C. Fisher mail

    mathew.fisher@imperial.ac.uk

    Affiliation: Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom

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  • Published: April 28, 2011
  • DOI: 10.1371/journal.ppat.1001343

About the Authors

Sitali P. Simwami, Daniel A. Henk, David M. Aanensen, Christl A. Donnelly, Matthew C. Fisher
Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College London, London, United Kingdom
Kantarawee Khayhan, Teun Boekhout, Ferry Hagen
CBS Fungal Biodiversity Centre, Utrecht, The Netherlands
Kantarawee Khayhan
Department of Microbiology and Parasitology, School of Medical Science, Naresuan University Phayao, Phayao, Thailand
Annemarie E. Brouwer
Department of General Internal Medicine and Nijmegen University Center for Infectious Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands
Annemarie E. Brouwer
St. Elisabeth Hospital, Tilburg, The Netherlands
Thomas S. Harrison
Department of Infectious Diseases, St George's Hospital Medical School, London, United Kingdom

Corresponding Author

Email: mathew.fisher@imperial.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SPS MCF. Performed the experiments: SPS KK FH AEB. Analyzed the data: SPS DAH CAD. Contributed reagents/materials/analysis tools: SPS DMA TB TSH. Wrote the paper: SPS MCF. MLST website creation: DMA.