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Research Article

The Clostridium difficile Cell Wall Protein CwpV is Antigenically Variable between Strains, but Exhibits Conserved Aggregation-Promoting Function

  • Catherine B. Reynolds,

    Affiliation: Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

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  • Jenny E. Emerson,

    Affiliation: Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

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  • Lucia de la Riva,

    Affiliation: Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

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  • Robert P. Fagan,

    Affiliation: Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

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  • Neil F. Fairweather mail

    n.fairweather@imperial.ac.uk

    Affiliation: Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

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  • Published: April 21, 2011
  • DOI: 10.1371/journal.ppat.1002024

About the Authors

Catherine B. Reynolds, Jenny E. Emerson, Lucia de la Riva, Robert P. Fagan, Neil F. Fairweather
Division of Cell and Molecular Biology, Centre for Molecular Microbiology and Infection, Imperial College London, London, United Kingdom

Corresponding Author

Email: n.fairweather@imperial.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NFF CBR JEE LdlR RPF. Performed the experiments: CBR JEE LdlR RPF. Analyzed the data: CBR JEE LdlR RPF NFF. Wrote the paper: CBR RPF NFF.