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Research Article

Dual Function of the NK Cell Receptor 2B4 (CD244) in the Regulation of HCV-Specific CD8+ T Cells

  • Verena Schlaphoff,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Sebastian Lunemann,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Pothakamuri Venkata Suneetha,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Jerzy Jaroszewicz,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Jan Grabowski,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Julia Dietz,

    Affiliation: J. W. Goethe University Hospital, Frankfurt am Main, Germany

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  • Fabian Helfritz,

    Affiliation: Department for Visceral Surgery, Hannover Medical School, Hannover, Germany

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  • Hueseyin Bektas,

    Affiliation: Department for Visceral Surgery, Hannover Medical School, Hannover, Germany

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  • Christoph Sarrazin,

    Affiliation: J. W. Goethe University Hospital, Frankfurt am Main, Germany

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  • Michael Peter Manns,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Markus Cornberg,

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Heiner Wedemeyer mail

    wedemeyer.heiner@mh-hannover.de

    Affiliation: Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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  • Published: May 19, 2011
  • DOI: 10.1371/journal.ppat.1002045

About the Authors

Verena Schlaphoff, Sebastian Lunemann, Pothakamuri Venkata Suneetha, Jerzy Jaroszewicz, Jan Grabowski, Michael Peter Manns, Markus Cornberg, Heiner Wedemeyer
Department for Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany
Julia Dietz, Christoph Sarrazin
J. W. Goethe University Hospital, Frankfurt am Main, Germany
Fabian Helfritz, Hueseyin Bektas
Department for Visceral Surgery, Hannover Medical School, Hannover, Germany

Corresponding Author

Email: wedemeyer.heiner@mh-hannover.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VS MC HW. Performed the experiments: VS SL PVS JJ JG. Analyzed the data: VS SL MC HW. Contributed reagents/materials/analysis tools: JD FH HB CS. Wrote the paper: VS MPM MC HW.