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Research Article

HSV-2 Infection of Dendritic Cells Amplifies a Highly Susceptible HIV-1 Cell Target

  • Elena Martinelli mail,

    emartinelli@popcouncil.org (EM); mrobbiani@popcouncil.org (MR)

    Affiliation: Center for Biomedical Research, Population Council, New York, New York, United States of America

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  • Hugo Tharinger,

    Affiliation: Center for Biomedical Research, Population Council, New York, New York, United States of America

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  • Ines Frank,

    Affiliation: Center for Biomedical Research, Population Council, New York, New York, United States of America

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  • James Arthos,

    Affiliation: Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Michael Piatak Jr.,

    Affiliation: AIDS and Cancer Virus Program, SAIC-Frederick, Inc., National Cancer Institute, Frederick, Maryland, Unites States of America

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  • Jeffrey D. Lifson,

    Affiliation: AIDS and Cancer Virus Program, SAIC-Frederick, Inc., National Cancer Institute, Frederick, Maryland, Unites States of America

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  • James Blanchard,

    Affiliation: Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, United States of America

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  • Agegnehu Gettie,

    Affiliation: Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, Unites States of America

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  • Melissa Robbiani mail

    emartinelli@popcouncil.org (EM); mrobbiani@popcouncil.org (MR)

    Affiliation: Center for Biomedical Research, Population Council, New York, New York, United States of America

    X
  • Published: June 30, 2011
  • DOI: 10.1371/journal.ppat.1002109

About the Authors

Elena Martinelli, Hugo Tharinger, Ines Frank, Melissa Robbiani
Center for Biomedical Research, Population Council, New York, New York, United States of America
James Arthos
Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
Michael Piatak Jr., Jeffrey D. Lifson
AIDS and Cancer Virus Program, SAIC-Frederick, Inc., National Cancer Institute, Frederick, Maryland, Unites States of America
James Blanchard
Tulane National Primate Research Center, Tulane University Health Sciences Center, Covington, Louisiana, United States of America
Agegnehu Gettie
Aaron Diamond AIDS Research Center, Rockefeller University, New York, New York, Unites States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EM MR. Performed the experiments: EM HT IF. Analyzed the data: EM MR. Contributed reagents/materials/analysis tools: MPJ JDL JB AG JA. Wrote the paper: EM MR. Contributed to the discussion: JA.