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Research Article

A Dynamic Landscape for Antibody Binding Modulates Antibody-Mediated Neutralization of West Nile Virus

  • Kimberly A. Dowd equal contributor,

    equal contributor Contributed equally to this work with: Kimberly A. Dowd, Christiane A. Jost

    Affiliation: Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

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  • Christiane A. Jost equal contributor,

    equal contributor Contributed equally to this work with: Kimberly A. Dowd, Christiane A. Jost

    Affiliation: Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Anna P. Durbin,

    Affiliation: Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

    X
  • Stephen S. Whitehead,

    Affiliation: Laboratory of Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Theodore C. Pierson mail

    piersontc@mail.nih.gov

    Affiliation: Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

    X
  • Published: June 30, 2011
  • DOI: 10.1371/journal.ppat.1002111

About the Authors

Kimberly A. Dowd, Christiane A. Jost, Theodore C. Pierson
Viral Pathogenesis Section, Laboratory of Viral Diseases, National Institutes of Health, Bethesda, Maryland, United States of America
Anna P. Durbin
Center for Immunization Research, Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America
Stephen S. Whitehead
Laboratory of Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

Corresponding Author

Email: piersontc@mail.nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KAD CAJ TCP. Performed the experiments: KAD CAJ. Analyzed the data: KAD CAJ TCP. Contributed reagents/materials/analysis tools: APD SSW. Wrote the paper: KAD CAJ TCP.