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Research Article

An Interaction between KSHV ORF57 and UIF Provides mRNA-Adaptor Redundancy in Herpesvirus Intronless mRNA Export

  • Brian R. Jackson,

    Affiliations: Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom

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  • James R. Boyne,

    Affiliation: Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom

    Current address: Division of Biomedical Sciences, School of Life Sciences, University of Bradford, Bradford, United Kingdom.

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  • Marko Noerenberg,

    Affiliations: Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom

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  • Adam Taylor,

    Affiliations: Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom

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  • Guillaume M. Hautbergue,

    Affiliation: Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

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  • Matthew J. Walsh,

    Affiliation: Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

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  • Rachel Wheat,

    Affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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  • David J. Blackbourn,

    Affiliation: School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

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  • Stuart A. Wilson,

    Affiliation: Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom

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  • Adrian Whitehouse mail

    a.whitehouse@leeds.ac.uk

    Affiliations: Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom, Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom

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  • Published: July 21, 2011
  • DOI: 10.1371/journal.ppat.1002138

About the Authors

Brian R. Jackson, James R. Boyne, Marko Noerenberg, Adam Taylor, Adrian Whitehouse
Institute of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom
Brian R. Jackson, Marko Noerenberg, Adam Taylor, Adrian Whitehouse
Astbury Centre for Structural Molecular Biology, University of Leeds, Leeds, United Kingdom
Guillaume M. Hautbergue, Matthew J. Walsh, Stuart A. Wilson
Department of Molecular Biology and Biotechnology, University of Sheffield, Sheffield, United Kingdom
Rachel Wheat, David J. Blackbourn
School of Cancer Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom

Corresponding Author

Email: a.whitehouse@leeds.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BRJ DJB SAW AW. Performed the experiments: BRJ JRB MN AT GMH MJW RW AW. Analyzed the data: BRJ AW. Contributed reagents/materials/analysis tools: AW DJB SAW. Worte the paper: BRJ AW.