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Research Article

The Trypanosoma cruzi Protease Cruzain Mediates Immune Evasion

  • Patricia S. Doyle mail,

    Patricia.Doyle-Engel@ucsf.edu

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

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  • Yuan M. Zhou,

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

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  • Ivy Hsieh,

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

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  • Doron C. Greenbaum,

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

    Current address: Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America.

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  • James H. McKerrow,

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

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  • Juan C. Engel

    Affiliation: Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

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  • Published: September 01, 2011
  • DOI: 10.1371/journal.ppat.1002139

About the Authors

Patricia S. Doyle, Yuan M. Zhou, Ivy Hsieh, Doron C. Greenbaum, James H. McKerrow, Juan C. Engel
Tropical Disease Research Unit and Sandler Center for Drug Discovery, Department of Pathology, University of California, San Francisco, California, United States of America

Corresponding Author

Email: Patricia.Doyle-Engel@ucsf.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: PSD JCE. Performed the experiments: PSD YMZ IH JCE. Analyzed the data: PSD JCE JHM DCG. Contributed reagents/materials/analysis tools: DCG. Wrote the paper: PSD.