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Research Article

Elevated 17β-Estradiol Protects Females from Influenza A Virus Pathogenesis by Suppressing Inflammatory Responses

  • Dionne P. Robinson,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Maria E. Lorenzo,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • William Jian,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Sabra L. Klein mail

    saklein@jhsph.edu

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

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  • Published: July 28, 2011
  • DOI: 10.1371/journal.ppat.1002149

About the Authors

Dionne P. Robinson, Maria E. Lorenzo, William Jian, Sabra L. Klein
W. Harry Feinstone Department of Molecular Microbiology and Immunology, The Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, United States of America

Corresponding Author

Email: saklein@jhsph.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DPR SLK. Performed the experiments: DPR MEL WJ. Analyzed the data: DPR SLK. Wrote the paper: DPR SLK.