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Research Article

Crystallography of a Lewis-Binding Norovirus, Elucidation of Strain-Specificity to the Polymorphic Human Histo-Blood Group Antigens

  • Yutao Chen equal contributor,

    equal contributor Contributed equally to this work with: Yutao Chen, Ming Tan

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    X
  • Ming Tan equal contributor,

    equal contributor Contributed equally to this work with: Yutao Chen, Ming Tan

    Affiliations: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

    X
  • Ming Xia,

    Affiliation: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

    X
  • Ning Hao,

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    X
  • Xuejun C. Zhang,

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    X
  • Pengwei Huang,

    Affiliation: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America

    X
  • Xi Jiang mail,

    jason.jiang@cchmc.org (XJ); lixm@sun5.ibp.ac.cn (XL)

    Affiliations: Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

    X
  • Xuemei Li mail,

    jason.jiang@cchmc.org (XJ); lixm@sun5.ibp.ac.cn (XL)

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    X
  • Zihe Rao

    Affiliation: National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China

    X
  • Published: July 21, 2011
  • DOI: 10.1371/journal.ppat.1002152

About the Authors

Yutao Chen, Ning Hao, Xuejun C. Zhang, Xuemei Li, Zihe Rao
National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China
Ming Tan, Ming Xia, Pengwei Huang, Xi Jiang
Division of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America
Ming Tan, Xi Jiang
University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XJ XL MT XCZ ZR. Performed the experiments: YC MT MX NH PH. Analyzed the data: YC MT XCZ XJ XL ZR. Contributed reagents/materials/analysis tools: MT XJ XCZ XL. Wrote the paper: YC MT XCZ XJ XL.