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Research Article

Crystal Structure of Reovirus Attachment Protein σ1 in Complex with Sialylated Oligosaccharides

  • Dirk M. Reiter,

    Affiliation: Interfaculty Institute of Biochemistry, University of Tuebingen, Tuebingen, Germany

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  • Johnna M. Frierson,

    Affiliations: Departments of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Elizabeth E. Halvorson,

    Affiliations: Departments of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    Current address: Department of Pediatrics, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America.

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  • Takeshi Kobayashi,

    Affiliations: Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

    Current address: Institute for Virus Research, Kyoto University, Kyoto, Japan.

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  • Terence S. Dermody mail,

    thilo.stehle@uni-tuebingen.de (TS); terry.dermody@vanderbilt.edu (TSD)

    Affiliations: Departments of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Thilo Stehle mail

    thilo.stehle@uni-tuebingen.de (TS); terry.dermody@vanderbilt.edu (TSD)

    Affiliations: Interfaculty Institute of Biochemistry, University of Tuebingen, Tuebingen, Germany, Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

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  • Published: August 04, 2011
  • DOI: 10.1371/journal.ppat.1002166

About the Authors

Dirk M. Reiter, Thilo Stehle
Interfaculty Institute of Biochemistry, University of Tuebingen, Tuebingen, Germany
Johnna M. Frierson, Elizabeth E. Halvorson, Terence S. Dermody
Departments of Pathology, Microbiology, and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Johnna M. Frierson, Elizabeth E. Halvorson, Takeshi Kobayashi, Terence S. Dermody
Elizabeth B. Lamb Center for Pediatric Research, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
Takeshi Kobayashi, Terence S. Dermody, Thilo Stehle
Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DMR JMF TSD TS. Performed the experiments: DMR JMF EEH TK. Analyzed the data: DMR JMF EEH TK TSD TS. Wrote the paper: DMR JMF TSD TS.