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Research Article

Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration

  • Lihong Zhou equal contributor,

    equal contributor Contributed equally to this work with: Lihong Zhou, Elena Sokolskaja

    Affiliations: Wohl Virion Centre, Division of Infection & Immunity, University College London, London, United Kingdom, MRC Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London, United Kingdom

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  • Elena Sokolskaja equal contributor,

    equal contributor Contributed equally to this work with: Lihong Zhou, Elena Sokolskaja

    Affiliations: Wohl Virion Centre, Division of Infection & Immunity, University College London, London, United Kingdom, MRC Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London, United Kingdom

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  • Clare Jolly,

    Affiliations: Wohl Virion Centre, Division of Infection & Immunity, University College London, London, United Kingdom, MRC Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London, United Kingdom

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  • William James,

    Affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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  • Sally A. Cowley,

    Affiliation: Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

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  • Ariberto Fassati mail

    a.fassati@ucl.ac.uk

    Affiliations: Wohl Virion Centre, Division of Infection & Immunity, University College London, London, United Kingdom, MRC Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London, United Kingdom

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  • Published: August 25, 2011
  • DOI: 10.1371/journal.ppat.1002194

About the Authors

Lihong Zhou, Elena Sokolskaja, Clare Jolly, Ariberto Fassati
Wohl Virion Centre, Division of Infection & Immunity, University College London, London, United Kingdom
Lihong Zhou, Elena Sokolskaja, Clare Jolly, Ariberto Fassati
MRC Centre for Medical Molecular Virology, Division of Infection & Immunity, University College London, London, United Kingdom
William James, Sally A. Cowley
Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

Corresponding Author

Email: a.fassati@ucl.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LZ ES CJ WJ SAC AF. Performed the experiments: LZ ES CJ SAC AF. Analyzed the data: LZ ES CJ AF. Contributed reagents/materials/analysis tools: SAC WJ. Wrote the paper: AF.