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Research Article

The Human Papillomavirus E6 Oncogene Represses a Cell Adhesion Pathway and Disrupts Focal Adhesion through Degradation of TAp63β upon Transformation

  • Youcef Ben Khalifa,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Sébastien Teissier,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Meng-Kwang Marcus Tan,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Quang Tien Phan,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Mathieu Daynac,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Wei Qi Wong,

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Françoise Thierry mail

    francoise.thierry@imb.a-star.edu.sg

    Affiliation: Institute of Medical Biology, A*STAR, Singapore

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  • Published: September 29, 2011
  • DOI: 10.1371/journal.ppat.1002256

About the Authors

Youcef Ben Khalifa, Sébastien Teissier, Meng-Kwang Marcus Tan, Quang Tien Phan, Mathieu Daynac, Wei Qi Wong, Françoise Thierry
Institute of Medical Biology, A*STAR, Singapore

Corresponding Author

Email: francoise.thierry@imb.a-star.edu.sg

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YBK ST FT. Performed the experiments: YBK ST M-KMT QTP MD WQW. Analyzed the data: YBK ST M-KMT MD FT. Wrote the paper: YBK FT.