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Research Article

A Trigger Enzyme in Mycoplasma pneumoniae: Impact of the Glycerophosphodiesterase GlpQ on Virulence and Gene Expression

  • Sebastian R. Schmidl,

    Affiliation: Department of General Microbiology, Georg-August-University Göttingen, Göttingen, Germany

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  • Andreas Otto,

    Affiliation: Institut für Mikrobiologie und Molekularbiologie, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany

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  • Maria Lluch-Senar,

    Affiliation: Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain

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  • Jaume Piñol,

    Affiliation: Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain

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  • Julia Busse,

    Affiliation: Department of General Microbiology, Georg-August-University Göttingen, Göttingen, Germany

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  • Dörte Becher,

    Affiliation: Institut für Mikrobiologie und Molekularbiologie, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany

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  • Jörg Stülke mail

    jstuelk@gwdg.de

    Affiliation: Department of General Microbiology, Georg-August-University Göttingen, Göttingen, Germany

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  • Published: September 22, 2011
  • DOI: 10.1371/journal.ppat.1002263

About the Authors

Sebastian R. Schmidl, Julia Busse, Jörg Stülke
Department of General Microbiology, Georg-August-University Göttingen, Göttingen, Germany
Andreas Otto, Dörte Becher
Institut für Mikrobiologie und Molekularbiologie, Ernst-Moritz-Arndt-Universität Greifswald, Greifswald, Germany
Maria Lluch-Senar, Jaume Piñol
Institut de Biotecnologia i Biomedicina and Departament de Bioquímica i Biologia Molecular, Universitat Autònoma de Barcelona, Barcelona, Spain

Corresponding Author

Email: jstuelk@gwdg.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SRS JP JS. Performed the experiments: SRS AO MLS JB. Analyzed the data: SRS MLS DB JS. Wrote the paper: SRS JS.