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Research Article

Strain Specific Resistance to Murine Scrapie Associated with a Naturally Occurring Human Prion Protein Polymorphism at Residue 171

  • James F. Striebel,

    Affiliation: Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

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  • Brent Race,

    Affiliation: Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

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  • Kimberly D. Meade-White,

    Affiliation: Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

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  • Rachel LaCasse,

    Affiliation: Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

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  • Bruce Chesebro mail

    bchesebro@nih.gov

    Affiliation: Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

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  • Published: September 29, 2011
  • DOI: 10.1371/journal.ppat.1002275

About the Authors

James F. Striebel, Brent Race, Kimberly D. Meade-White, Rachel LaCasse, Bruce Chesebro
Laboratory of Persistent Viral Diseases and Rocky Mountain Laboratories, National Institute of Allergy and Infectious Diseases, Hamilton, Montana, United States of America

Corresponding Author

Email: bchesebro@nih.gov

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JFS BC. Performed the experiments: JFS KDMW BR RL. Analyzed the data: JFS BC. Contributed reagents/materials/analysis tools: BR. Wrote the paper: JFS BC KDMW.