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Research Article

The Herpes Simplex Virus-1 Transactivator Infected Cell Protein-4 Drives VEGF-A Dependent Neovascularization

  • Todd Wuest,

    Affiliations: Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Min Zheng,

    Affiliation: Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Stacey Efstathiou,

    Affiliation: Department of Pathology, University of Cambridge, Cambridge, United Kingdom

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  • William P. Halford,

    Affiliation: Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America

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  • Daniel J. J. Carr mail

    Dan-Carr@ouhsc.edu

    Affiliations: Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

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  • Published: October 06, 2011
  • DOI: 10.1371/journal.ppat.1002278

About the Authors

Todd Wuest, Daniel J. J. Carr
Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Todd Wuest, Min Zheng, Daniel J. J. Carr
Department of Ophthalmology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America
Stacey Efstathiou
Department of Pathology, University of Cambridge, Cambridge, United Kingdom
William P. Halford
Department of Microbiology and Immunology, Southern Illinois University School of Medicine, Springfield, Illinois, United States of America

Corresponding Author

Email: Dan-Carr@ouhsc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: TW DJJC. Performed the experiments: TW MZ. Analyzed the data: TW. Contributed reagents/materials/analysis tools: SE WPH. Wrote the paper: TW DJJC.