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Research Article

A Viral Nuclear Noncoding RNA Binds Re-localized Poly(A) Binding Protein and Is Required for Late KSHV Gene Expression

  • Sumit Borah,

    Affiliation: Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, Connecticut, United States of America

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  • Nicole Darricarrère,

    Affiliation: Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America

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  • Alicia Darnell,

    Affiliation: Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, Connecticut, United States of America

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  • Jinjong Myoung,

    Affiliation: Department of Microbiology and Immunology, Howard Hughes Medical Institute, University of California, San Francisco, California, United States of America

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  • Joan A. Steitz mail

    joan.steitz@yale.edu

    Affiliation: Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, Connecticut, United States of America

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  • Published: October 13, 2011
  • DOI: 10.1371/journal.ppat.1002300

About the Authors

Sumit Borah, Alicia Darnell, Joan A. Steitz
Department of Molecular Biophysics and Biochemistry, Howard Hughes Medical Institute, Yale University, New Haven, Connecticut, United States of America
Nicole Darricarrère
Department of Cell Biology, Yale University School of Medicine, New Haven, Connecticut, United States of America
Jinjong Myoung
Department of Microbiology and Immunology, Howard Hughes Medical Institute, University of California, San Francisco, California, United States of America

Corresponding Author

Email: joan.steitz@yale.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SB JAS. Performed the experiments: SB ND AD. Analyzed the data: SB ND AD JAS. Contributed reagents/materials/analysis tools: SB JM. Wrote the paper: SB JAS.