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Research Article

Sequential Adaptive Mutations Enhance Efficient Vector Switching by Chikungunya Virus and Its Epidemic Emergence

  • Konstantin A. Tsetsarkin,

    Affiliation: Institute for Human Infections and Immunity, Center for Tropical Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Scott C. Weaver mail

    sweaver@utmb.edu

    Affiliation: Institute for Human Infections and Immunity, Center for Tropical Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

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  • Published: December 08, 2011
  • DOI: 10.1371/journal.ppat.1002412

About the Authors

Konstantin A. Tsetsarkin, Scott C. Weaver
Institute for Human Infections and Immunity, Center for Tropical Diseases, and Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America

Corresponding Author

Email: sweaver@utmb.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KAT SCW. Performed the experiments: KAT. Analyzed the data: KAT SCW. Wrote the paper: KAT SCW.