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Research Article

Two Distinct Coagulase-Dependent Barriers Protect Staphylococcus aureus from Neutrophils in a Three Dimensional in vitro Infection Model

  • Christoph Guggenberger,

    Affiliation: Max von Pettenkofer-Institut, Ludwig-Maximilians-University of Munich (LMU), Munich, Germany

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  • Christiane Wolz,

    Affiliation: Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany

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  • Julie A. Morrissey,

    Affiliation: Department of Genetics, University of Leicester, Leicester, United Kingdom

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  • Jürgen Heesemann mail

    heesemann@mvp.uni-muenchen.de

    Affiliation: Max von Pettenkofer-Institut, Ludwig-Maximilians-University of Munich (LMU), Munich, Germany

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  • Published: January 12, 2012
  • DOI: 10.1371/journal.ppat.1002434

About the Authors

Christoph Guggenberger, Jürgen Heesemann
Max von Pettenkofer-Institut, Ludwig-Maximilians-University of Munich (LMU), Munich, Germany
Christiane Wolz
Interfaculty Institute of Microbiology and Infection Medicine, University of Tübingen, Tübingen, Germany
Julie A. Morrissey
Department of Genetics, University of Leicester, Leicester, United Kingdom

Corresponding Author

Email: heesemann@mvp.uni-muenchen.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CG JH. Performed the experiments: CG. Analyzed the data: CG JH CW. Contributed reagents/materials/analysis tools: CG JH CW JAM. Wrote the paper: CG JH.