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Research Article

Ce-Duox1/BLI-3 Generated Reactive Oxygen Species Trigger Protective SKN-1 Activity via p38 MAPK Signaling during Infection in C. elegans

  • Ransome van der Hoeven,

    Affiliation: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Katie C. McCallum,

    Affiliation: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Melissa R. Cruz,

    Affiliation: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Danielle A. Garsin mail

    Danielle.A.Garsin@uth.tmc.edu

    Affiliation: Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

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  • Published: December 22, 2011
  • DOI: 10.1371/journal.ppat.1002453

About the Authors

Ransome van der Hoeven, Katie C. McCallum, Melissa R. Cruz, Danielle A. Garsin
Department of Microbiology and Molecular Genetics, The University of Texas Health Science Center at Houston, Houston, Texas, United States of America

Corresponding Author

Email: Danielle.A.Garsin@uth.tmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DAG RvdH KCM. Performed the experiments: RvdH KCM MRC. Analyzed the data: DAG RvdH KCM MRC. Wrote the paper: DAG RvdH.