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Research Article

HIV-1 Superinfection in Women Broadens and Strengthens the Neutralizing Antibody Response

  • Valerie Cortez,

    Affiliations: Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America, Department of Epidemiology, University of Washington, Seattle, Washington, United States of America, Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Katherine Odem-Davis,

    Affiliation: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • R. Scott McClelland,

    Affiliation: Department of Epidemiology, University of Washington, Seattle, Washington, United States of America

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  • Walter Jaoko,

    Affiliation: Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya

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  • Julie Overbaugh mail

    joverbau@fhcrc.org

    Affiliation: Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Published: March 29, 2012
  • DOI: 10.1371/journal.ppat.1002611

About the Authors

Valerie Cortez
Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, United States of America
Valerie Cortez, R. Scott McClelland
Department of Epidemiology, University of Washington, Seattle, Washington, United States of America
Valerie Cortez, Katherine Odem-Davis, Julie Overbaugh
Division of Human Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Walter Jaoko
Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya

Corresponding Author

Email: joverbau@fhcrc.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JO RSM. Performed the experiments: VC. Analyzed the data: VC KO-D. Contributed reagents/materials/analysis tools: WJ. Wrote the paper: VC RSM JO. Provided comments on the manuscript: KO-D WJ. Oversaw the laboratory aspects of this study related to the cohort: WJ. Oversaw clinical aspects of the cohort, including directing clinical monitoring and follow-up: RSM. Oversaw all aspects of this research project: JO.