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Research Article

Small-Molecule Inhibitors of Dengue-Virus Entry

  • Aaron G. Schmidt,

    Affiliation: Jack and Eileen Connors Laboratory of Structural Biology, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Kyungae Lee,

    Affiliation: New England Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (NERCE/BEID), Harvard Medical School, Boston, Massachusetts, United States of America

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  • Priscilla L. Yang,

    Affiliation: Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Stephen C. Harrison mail

    harrison@crystal.harvard.edu

    Affiliations: Jack and Eileen Connors Laboratory of Structural Biology, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America, Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002627

About the Authors

Aaron G. Schmidt, Stephen C. Harrison
Jack and Eileen Connors Laboratory of Structural Biology, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, United States of America
Kyungae Lee
New England Regional Center of Excellence in Biodefense and Emerging Infectious Diseases (NERCE/BEID), Harvard Medical School, Boston, Massachusetts, United States of America
Priscilla L. Yang
Department of Microbiology and Molecular Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
Stephen C. Harrison
Howard Hughes Medical Institute, Harvard Medical School, Boston, Massachusetts, United States of America

Corresponding Author

Email: harrison@crystal.harvard.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AGS SCH. Performed the experiments: AGS KL. Analyzed the data: AGS KL PLY SCH. Contributed reagents/materials/analysis tools: KL PLY SCH. Wrote the paper: AGS KL PLY SCH.