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Research Article

Membrane Damage during Listeria monocytogenes Infection Triggers a Caspase-7 Dependent Cytoprotective Response

  • Sara K. B. Cassidy,

    Affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Jon A. Hagar,

    Affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Thirumala Devi Kanneganti,

    Affiliation: Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America

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  • Luigi Franchi,

    Affiliation: Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Gabriel Nuñez,

    Affiliation: Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Mary X. D. O'Riordan mail

    oriordan@umich.edu

    Affiliation: Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

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  • Published: July 12, 2012
  • DOI: 10.1371/journal.ppat.1002628

About the Authors

Sara K. B. Cassidy, Jon A. Hagar, Mary X. D. O'Riordan
Department of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
Thirumala Devi Kanneganti
Department of Immunology, St. Jude Children's Research Hospital, Memphis, Tennessee, United States of America
Luigi Franchi, Gabriel Nuñez
Department of Pathology and Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan, United States of America

Corresponding Author

Email: oriordan@umich.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SKBC JAH MXDO. Performed the experiments: SKBC JAH. Analyzed the data: SKBC MXDO. Contributed reagents/materials/analysis tools: TDK LF GN. Wrote the paper: SKBC MXDO.