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Research Article

Cell-Cell Transmission Enables HIV-1 to Evade Inhibition by Potent CD4bs Directed Antibodies

  • Irene A. Abela equal contributor,

    equal contributor Contributed equally to this work with: Irene A. Abela, Livia Berlinger

    Affiliations: Institute of Medical Virology, University of Zurich, Zurich, Switzerland, PhD Program in Microbiology and Immunology, University of Zurich, Zurich, Switzerland, MD-PhD Program, University of Zurich, Zurich, Switzerland

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  • Livia Berlinger equal contributor,

    equal contributor Contributed equally to this work with: Irene A. Abela, Livia Berlinger

    Affiliation: Institute of Medical Virology, University of Zurich, Zurich, Switzerland

    Current address: Bioanalytica AG, Lucerne, Switzerland

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  • Merle Schanz,

    Affiliations: Institute of Medical Virology, University of Zurich, Zurich, Switzerland, PhD Program in Microbiology and Immunology, University of Zurich, Zurich, Switzerland

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  • Lucy Reynell,

    Affiliations: Institute of Medical Virology, University of Zurich, Zurich, Switzerland, PhD Program in Microbiology and Immunology, University of Zurich, Zurich, Switzerland

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  • Huldrych F. Günthard,

    Affiliation: Division of Infectious Diseases, University Hospital Zurich, University of Zurich, Zurich, Switzerland

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  • Peter Rusert,

    Affiliation: Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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  • Alexandra Trkola mail

    trkola.alexandra@virology.uzh.ch

    Affiliation: Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002634

About the Authors

Irene A. Abela, Livia Berlinger, Merle Schanz, Lucy Reynell, Peter Rusert, Alexandra Trkola
Institute of Medical Virology, University of Zurich, Zurich, Switzerland
Irene A. Abela, Merle Schanz, Lucy Reynell
PhD Program in Microbiology and Immunology, University of Zurich, Zurich, Switzerland
Irene A. Abela
MD-PhD Program, University of Zurich, Zurich, Switzerland
Huldrych F. Günthard
Division of Infectious Diseases, University Hospital Zurich, University of Zurich, Zurich, Switzerland

Corresponding Author

Email: trkola.alexandra@virology.uzh.ch

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IAA LB AT. Performed the experiments: IAA LB MS LR PR. Analyzed the data: IAA LB PR HFG AT. Wrote the paper: IAA LB LR HFG AT.