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Research Article

Matrix Metalloprotease 9 Mediates Neutrophil Migration into the Airways in Response to Influenza Virus-Induced Toll-Like Receptor Signaling

  • Linda M. Bradley equal contributor,

    equal contributor Contributed equally to this work with: Linda M. Bradley, Mia F. Douglass

    Affiliation: Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Mia F. Douglass equal contributor,

    equal contributor Contributed equally to this work with: Linda M. Bradley, Mia F. Douglass

    Affiliation: Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Dhrubamitra Chatterjee,

    Affiliation: Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

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  • Shizuo Akira,

    Affiliation: Laboratory of Host Defense, World Premier International Immunology Frontier Research Center, and Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

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  • Bas J. G. Baaten mail

    bbaaten@sanfordburnham.org

    Affiliation: Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America

    X
  • Published: April 05, 2012
  • DOI: 10.1371/journal.ppat.1002641

About the Authors

Linda M. Bradley, Mia F. Douglass, Dhrubamitra Chatterjee, Bas J. G. Baaten
Infectious and Inflammatory Disease Center, Sanford-Burnham Medical Research Institute, La Jolla, California, United States of America
Shizuo Akira
Laboratory of Host Defense, World Premier International Immunology Frontier Research Center, and Department of Host Defense, Research Institute for Microbial Diseases, Osaka University, Osaka, Japan

Corresponding Author

Email: bbaaten@sanfordburnham.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: BJGB. Performed the experiments: BJGB MFD DC. Analyzed the data: BJGB. Contributed reagents/materials/analysis tools: LMB SA. Wrote the paper: BJGB MFD LMB.