# wombat urls ß PLOS Pathogens: Induction of GADD34 Is Necessary for dsRNA-Dependent Interferon-β Production and Participates in the Control of Chikungunya Virus Infection
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Research Article

Induction of GADD34 Is Necessary for dsRNA-Dependent Interferon-β Production and Participates in the Control of Chikungunya Virus Infection

  • Giovanna Clavarino equal contributor,

    equal contributor Contributed equally to this work with: Giovanna Clavarino, Nuno Cláudio, Thérèse Couderc

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Nuno Cláudio equal contributor,

    equal contributor Contributed equally to this work with: Giovanna Clavarino, Nuno Cláudio, Thérèse Couderc

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Thérèse Couderc equal contributor,

    equal contributor Contributed equally to this work with: Giovanna Clavarino, Nuno Cláudio, Thérèse Couderc

    Affiliations: Institut Pasteur, ‘Microbes and host barriers’ Group, Paris, France, Inserm, Equipe avenir U604, Paris, France

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  • Alexandre Dalet,

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Delphine Judith,

    Affiliations: Institut Pasteur, ‘Microbes and host barriers’ Group, Paris, France, Inserm, Equipe avenir U604, Paris, France

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  • Voahirana Camosseto,

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Enrico K. Schmidt,

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Till Wenger,

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

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  • Marc Lecuit,

    Affiliations: Institut Pasteur, ‘Microbes and host barriers’ Group, Paris, France, Inserm, Equipe avenir U604, Paris, France, Université Paris Descartes, Hôpital Necker-Enfants malades, Service des Maladies Infectieuses et Tropicales, Assistance Publique-Hôpitaux de Paris, Paris, France

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  • Evelina Gatti mail,

    gatti@ciml.univ-mrs.fr (EG) (EG); pierre@ciml.univ-mrs.fr (PP) (PP)

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

    These authors also contributed equally to this work.

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  • Philippe Pierre mail

    gatti@ciml.univ-mrs.fr (EG) (EG); pierre@ciml.univ-mrs.fr (PP) (PP)

    Affiliations: Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France, INSERM, U1104, Marseille, France, CNRS, UMR 7280, Marseille, France

    These authors also contributed equally to this work.

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  • Published: May 17, 2012
  • DOI: 10.1371/journal.ppat.1002708

About the Authors

Giovanna Clavarino, Nuno Cláudio, Alexandre Dalet, Voahirana Camosseto, Enrico K. Schmidt, Till Wenger, Evelina Gatti, Philippe Pierre
Centre d'Immunologie de Marseille-Luminy, UM2, Aix-Marseille Université, Marseille, France
Giovanna Clavarino, Nuno Cláudio, Alexandre Dalet, Voahirana Camosseto, Enrico K. Schmidt, Till Wenger, Evelina Gatti, Philippe Pierre
INSERM, U1104, Marseille, France
Giovanna Clavarino, Nuno Cláudio, Alexandre Dalet, Voahirana Camosseto, Enrico K. Schmidt, Till Wenger, Evelina Gatti, Philippe Pierre
CNRS, UMR 7280, Marseille, France
Thérèse Couderc, Delphine Judith, Marc Lecuit
Institut Pasteur, ‘Microbes and host barriers’ Group, Paris, France
Thérèse Couderc, Delphine Judith, Marc Lecuit
Inserm, Equipe avenir U604, Paris, France
Marc Lecuit
Université Paris Descartes, Hôpital Necker-Enfants malades, Service des Maladies Infectieuses et Tropicales, Assistance Publique-Hôpitaux de Paris, Paris, France

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: GC NC AD EG PP. Performed the experiments: GC TC NC AD DJ EKS TW VC. Analyzed the data: GC NC TC AD ML EG PP. Wrote the paper: GC NC AD ML EG PP.